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Review Article
A cell stress signaling model of fetal hemoglobin induction: what doesn't kill red blood cells may make them stronger Rodwell Mabaera, Rachel J. West, Sarah J. Conine, Elizabeth R. Macari, Chelsea D. Boyd, Cocav A. Engman, Christopher H. Lowrey pages 1057-1072 Abstract | Full Text | Full-Text PDF (782 KB)
Clinical Investigations
Fetal-maternal microchimerism in normal parous females and parous female cancer patients, 28 May 2008 Gary L. Gilmore, Bushra Haq, Richard K. Shadduck, Sri Lakshmi Jasthy, John Lister pages 1073-1077 Abstract | Full Text | Full-Text PDF (249 KB)
Outcomes of splenectomy in T-cell large granular lymphocyte leukemia with splenomegaly and cytopenia, 12 June 2008 Vivek Subbiah, Aaron D. Viny, Steven Rosenblatt, Brad Pohlman, Alan Lichtin, Jaroslaw P. Maciejewski pages 1078-1083 Abstract | Full Text | Full-Text PDF (201 KB)
Cytokines
AMD3100 synergizes with G-CSF to mobilize repopulating stem cells in Fanconi anemia knockout mice, 21 May 2008 Anna C. Pulliam, M. Joe Hobson, Samantha L. Ciccone, Yan Li, Shi Chen, Edward F. Srour, Feng-Chun Yang, Hal E. Broxmeyer, D. Wade Clapp pages 1084-1090 Abstract | Full Text | Full-Text PDF (433 KB)
Gene Therapy
Preventive and therapeutic effects of gene therapy using silica nanoparticles–binding of GM-CSF gene on white blood cell production in dogs with leukopenia, 12 June 2008 Eun Wha Choi, Hye Cheong Koo, Il Seob Shin, Young Jin Chae, Jong Hwa Lee, Sei Myoung Han, Seung Jun Lee, Dong Ha Bhang, Yong Ho Park, Chang Woo Lee, Hwa Young Youn pages 1091-1097 Abstract | Full Text | Full-Text PDF (548 KB)
General Hematopoiesis
Rapid and recurrent neutrophil mobilization regulated by T134, a CXCR4 peptide antagonist, 21 May 2008 Chandrasekar V. Iyer, Robert J. Evans, Qinyuan Lou, Datian Lin, Jian Wang, Wayne Kohn, Liang Zeng Yan, Shon Pulley, Sheng-Bin Peng pages 1098-1109 Abstract | Full Text | Full-Text PDF (714 KB)
E3 ligase FLRF (Rnf41) regulates differentiation of hematopoietic progenitors by governing steady-state levels of cytokine and retinoic acid receptors, 21 May 2008 Xin Jing, Jorge Infante, Ronald G. Nachtman, Roland Jurecic pages 1110-1120 Abstract | Full Text | Full-Text PDF (1306 KB)
Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin−CD34− cells, 18 June 2008 Masayoshi Kobune, Yutaka Kawano, Sho Takahashi, Kohichi Takada, Kazuyuki Murase, Satosi Iyama, Tsutomu Sato, Rishu Takimoto, Yoshiro Niitsu, Junji Kato pages 1121-1131 Abstract | Full Text | Full-Text PDF (1424 KB)
Hematological Malignancies
montalcino, A zebrafish model for variegate porphyria, 12 June 2008 Kimberly A. Dooley, Paula G. Fraenkel, Nathaniel B. Langer, Bettina Schmid, Alan J. Davidson, Gerhard Weber, Ken Chiang, Helen Foott, Caitlin Dwyer, Rebecca A. Wingert, Yi Zhou, Barry H. Paw, Leonard I. Zon, Tübingen 2000 Screen Consortium pages 1132-1142 Abstract | Full Text | Full-Text PDF (2251 KB)
Microenvironment
Bone marrow sinusoidal endothelial cells undergo nonapoptotic cell death and are replaced by proliferating sinusoidal cells in situ to maintain the vascular niche following lethal irradiation Xiao-Miao Li, Zhongbo Hu, Marda L. Jorgenson, John R. Wingard, William B. Slayton pages 1143-1156.e3 Abstract | Full Text | Full-Text PDF (6839 KB)
Stem Cell Biology
Parathyroid hormone effectively induces mobilization of progenitor cells without depletion of bone marrow, 27 May 2008 Stefan Brunner, Marc-Michael Zaruba, Bruno Huber, Robert David, Marcus Vallaster, Gerald Assmann, Josef Mueller-Hoecker, Wolfgang-Michael Franz pages 1157-1166 Abstract | Full Text | Full-Text PDF (914 KB)
Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3, 12 June 2008 Karl R. Karlsson, Sally Cowley, Fernando O. Martinez, Michael Shaw, Stephen L. Minger, William James pages 1167-1175 Abstract | Full Text | Full-Text PDF (1159 KB) | Supplementary Content
Effects of plating density and culture time on bone marrow stromal cell characteristics, 21 May 2008 Birgit Neuhuber, Sharon A. Swanger, Linda Howard, Alastair Mackay, Itzhak Fischer pages 1176-1185 Abstract | Full Text | Full-Text PDF (1223 KB)
Analysis of the temporal and concentration-dependent effects of BMP-4, VEGF, and TPO on development of embryonic stem cell–derived mesoderm and blood progenitors in a defined, serum-free media, 12 June 2008 Kelly A. Purpura, Jennifer Morin, Peter W. Zandstra pages 1186-1198 Abstract | Full Text | Full-Text PDF (1317 KB)
Differential expression of CD150 (SLAM) family receptors by human hematopoietic stem and progenitor cells, 21 May 2008 Jordi Sintes, Xavier Romero, Pedro Marin, Cox Terhorst, Pablo Engel pages 1199-1204 Abstract | Full Text | Full-Text PDF (518 KB)
Stem Cell Transplantation
Erythroid-lineage–specific engraftment in patients with severe hemoglobinopathy following allogeneic hematopoietic stem cell transplantation, 12 June 2008 Paul M. Armistead, Mehrdad Mohseni, Roslyn Gerwin, Emily C. Walsh, Masoud Iravani, Bahram Chahardouli, Shahrbano Rostami, Wandi Zhang, Donna Neuberg, John Rioux, Ardeshir Ghavamzadeh, Jerome Ritz, Joseph H. Antin, Catherine J. Wu pages 1205-1215 Abstract | Full Text | Full-Text PDF (687 KB)
Recovery from established graft-vs-host disease achieved by bone marrow transplantation from a third-party allogeneic donor, 03 July 2008 Yuki Taniguchi, Satoshi Yoshihara, Yoshihiko Hoshida, Takayuki Inoue, Tatsuya Fujioka, Kazuhiro Ikegame, Manabu Kawakami, Tomoki Masuda, Katsuyuki Aozasa, Ichiro Kawase, Hiroyasu Ogawa pages 1216-1225 Abstract | Full Text | Full-Text PDF (1005 KB)
Frontmatter
Editorial Board page A1 Full-Text PDF (95 KB)
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