Experimental Hematology
Volume 40, Issue 2 , Pages 166-174.e3, February 2012

Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk/Sh2b3 via Bcl-xL

  • Nao Suzuki

      Affiliations

    • Laboratory of Stem Cell Therapy, Center for Experimental Medicine, The Institute of Medical Science, University of Tokyo, Tokyo, Japan
    • Department of Immune Regulation, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan
  • ,
  • Satoshi Yamazaki

      Affiliations

    • Japan Science Technology Agency, Exploratory Research for Advanced Technology (ERATO) Nakauchi Stem Cell and Organ Regeneration Project, Tokyo, Japan
  • ,
  • Hideo Ema

      Affiliations

    • Laboratory of Stem Cell Therapy, Center for Experimental Medicine, The Institute of Medical Science, University of Tokyo, Tokyo, Japan
  • ,
  • Tomoyuki Yamaguchi

      Affiliations

    • Laboratory of Stem Cell Therapy, Center for Experimental Medicine, The Institute of Medical Science, University of Tokyo, Tokyo, Japan
    • Japan Science Technology Agency, Exploratory Research for Advanced Technology (ERATO) Nakauchi Stem Cell and Organ Regeneration Project, Tokyo, Japan
  • ,
  • Hiromitsu Nakauchi

      Affiliations

    • Laboratory of Stem Cell Therapy, Center for Experimental Medicine, The Institute of Medical Science, University of Tokyo, Tokyo, Japan
    • Japan Science Technology Agency, Exploratory Research for Advanced Technology (ERATO) Nakauchi Stem Cell and Organ Regeneration Project, Tokyo, Japan
    • Corresponding Author InformationOffprint requests to: Hiromitsu Nakauchi, M.D., Ph.D., Laboratory of Stem Cell Therapy, Center for Experimental Medicine, The Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
  • ,
  • Satoshi Takaki

      Affiliations

    • Department of Immune Regulation, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan
    • Corresponding Author InformationSatoshi Takaki, M.D., Ph.D., Department of Immune Regulation, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan

Received 31 August 2011; received in revised form 25 October 2011; accepted 9 November 2011. published online 21 November 2011.

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PII: S0301-472X(11)00546-7

doi:10.1016/j.exphem.2011.11.003

Experimental Hematology
Volume 40, Issue 2 , Pages 166-174.e3, February 2012