Experimental Hematology
Volume 38, Issue 8 , Pages 661-665, August 2010

Detection of differential mitotic cell age in bone marrow CD34+ cells from patients with myelodysplastic syndrome and acute leukemia by analysis of an epigenetic molecular clock DNA signature

  • Maximilian Mossner

      Affiliations

    • Department of Hematology, Oncology and Transfusion Medicine, Charité, University Hospital Benjamin Franklin, Berlin, Germany
    • Corresponding Author InformationOffprint requests to: Maximilian Mossner, B.Sc., Charité University Hospital, Campus Benjamin Franklin, Department of Hematology and Oncology, Hindenburgdamm 30, Berlin 12200, Germany
    • ,
  • Olaf Hopfer

      Affiliations

    • Department of Hematology, Oncology and Transfusion Medicine, Charité, University Hospital Benjamin Franklin, Berlin, Germany
    • ,
  • Daniel Nowak

      Affiliations

    • Department of Hematology and Oncology, University Hospital, Mannheim, Germany
    • ,
  • Claudia D. Baldus

      Affiliations

    • Department of Hematology, Oncology and Transfusion Medicine, Charité, University Hospital Benjamin Franklin, Berlin, Germany
    • ,
  • Uwe Neumann

      Affiliations

    • Department of Traumatology, Community Hospital, Reichenbach, Germany
    • ,
  • Anke Kmetsch

      Affiliations

    • Department of Hematology, Oncology and Transfusion Medicine, Charité, University Hospital Benjamin Franklin, Berlin, Germany
    • ,
  • Ouidad Benlasfer

      Affiliations

    • Department of Hematology, Oncology and Transfusion Medicine, Charité, University Hospital Benjamin Franklin, Berlin, Germany
    • ,
  • Thilo John

      Affiliations

    • Department of Traumatology, Charité, University Hospital Benjamin Franklin, Berlin, Germany
    • ,
  • Carsten Perka

      Affiliations

    • Department of Traumatology, Charité, University Hospital Campus Mitte, Berlin, Germany
    • ,
  • Eckhard Thiel

      Affiliations

    • Department of Hematology, Oncology and Transfusion Medicine, Charité, University Hospital Benjamin Franklin, Berlin, Germany
    • ,
  • Wolf-Karsten Hofmann

      Affiliations

    • Department of Hematology and Oncology, University Hospital, Mannheim, Germany

Received 7 January 2010; received in revised form 12 March 2010; accepted 16 March 2010. published online 16 April 2010.

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PII: S0301-472X(10)00146-3

doi:10.1016/j.exphem.2010.03.022

Experimental Hematology
Volume 38, Issue 8 , Pages 661-665, August 2010

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