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Experimental Hematology
Volume 38, Issue 8
, Pages 685-695
, August 2010
A potential activity of valproic acid in the stimulation of interleukin-3−mediated megakaryopoiesis and erythropoiesis
References
- . The mammalian epigenome. Cell. 2007;128:669–681
- . Epigenetic control. J Cell Physiol. 2009;219:243–250
- . Histone deacetylase inhibitors as anti-neoplastic agents. Cancer Lett. 2009;280:192–200
- . Prospects: histone deacetylase inhibitors. J Cell Biochem. 2005;96:293–304
- . HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics. Cell Res. 2007;17:195–211
- . Histone deacetylase inhibitors: a review of their clinical status as antineoplastic agents. Cancer Invest. 2005;23:635–642
- . Histone tail modifications and noncanonical functions of histones: perspectives in cancer epigenetics. Mol Cancer Ther. 2008;7:740–748
- . Epigenetic therapies in haematological malignancies: searching for true targets. Eur J Cancer. 2009;45:1137–1145
- Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J. 2001;20:6969–6978
- . Epigenetics in acute myeloid leukemia. Semin Oncol. 2008;35:378–387
- . The role of histone deacetylases (HDACs) in human cancer. Mol Oncol. 2007;1:19–25
- Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells. Cancer Res. 2005;65:2537–2541
- Histone deacetylase inhibitor valproic acid enhances the cytokine-induced expansion of human hematopoietic stem cells. Cancer Res. 2005;65:1505–1513
- . Histone deacetylase inhibitor treatment downregulates VLA-4 adhesion in hematopoietic stem cells and acute myeloid leukemia blast cells. Haematologica. 2008;93:443–446
- Valproic acid enhances the engraftability of human umbilical cord blood hematopoietic stem cells expanded under serum-free conditions. Eur J Haematol. 2009;82:124–132
- Inhibitors of histone deacetylases promote hematopoietic stem cell self-renewal. Cytotherapy. 2004;6:328–336
- Pleiotropic role of histone deacetylases in the regulation of human adult erythropoiesis. Br J Haematol. 2006;135:242–253
- . Transcriptional control of megakaryocyte development. Oncogene. 2007;26:6795–6802
- . GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages. Immunity. 2003;19:451–462
- A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell- derived primitive hematopoiesis. Blood. 2009;114:1506–1517
- . Erythroid and megakaryocytic transformation. Oncogene. 2007;26:6803–6815
- . Valproic acid as epigenetic cancer drug: preclinical, clinical and transcriptional effects on solid tumors. Cancer Treat Rev. 2008;34:206–222
- The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009;114:937–951
- Notch ligand Delta-1 differentially modulates the effects of gp130 activation on interleukin-6 receptor alpha-positive and -negative human hematopoietic progenitors. Cancer Sci. 2007;98:1597–1603
- Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis. Blood. 1994;84:1085–1097
- . The structural and functional basis of cytokine receptor activation: lessons from the common beta subunit of the granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 receptors. Blood. 1997;89:1471–1482
- Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors. Stem Cells. 1998;16:301–313
- . Cell surface antigen expression in human erythroid progenitors: erythroid and megakaryocytic markers. Leuk Lymphoma. 1994;13:401–409
- . In vitro expansion of human cord blood CD36+ erythroid progenitors: temporal changes in gene and protein expression. Exp Hematol. 2003;31:760–769
- Thrombospondin-1 inhibits in vitro megakaryocytopoiesis via CD36. Thromb Res. 2003;109:47–54
- . Serum-free medium allows the optimal growth of human megakaryocyte progenitors compared with human plasma supplemented cultures: role of TGF beta. Stem Cells. 1993;11:120–129
- Ex vivo expansion of CD34+/CD41+ late progenitors from enriched peripheral blood CD34+ cells. Ann Hematol. 2000;79:13–19
- . GATA1 in normal and malignant hematopoiesis. Semin Cell Dev Biol. 2005;16:137–147
- . Gene expression regulation and domain function of hematopoietic GATA factors. Semin Cell Dev Biol. 2005;16:129–136
- . Dysregulation of the C/EBP Differentiation Pathway in Human Cancer. J Clin Oncol. 2009;27:619–628
- . Hematologic toxicity of sodium valproate. J Pediatr Hematol Oncol. 2000;22:62–65
- A putative role for histone deacetylase in the differentiation of human erythroid cells. Int J Oncol. 2005;27:743–748
- . A phase I/II study of sequential interleukin-3 and granulocyte-macrophage colony-stimulating factor in myelodysplastic syndromes. Blood. 1994;83:357–360
- . A phase I/II study of interleukin-3 in patients with aplastic anemia and myelodysplasia. Exp Hematol. 1994;22:875–880
- Treatment with very low-dose GM-CSF in myelodysplastic syndromes with neutropenia. A report on 28 cases. Leukemia. 1994;8:1458–1462
- . Interleukin-3 in hematology and oncology: current state of knowledge and future directions. Cytokines Cell Mol Ther. 1999;5:87–95
- . Hematopoietic growth factors in the treatment of acquired bone marrow failure states. Semin Hematol. 2007;44:138–147
- Erythropoietin and granulocyte-colony stimulating factor treatment associated with improved survival in myelodysplastic syndrome. J Clin Oncol. 2008;26:3607–3613
- . An assessment of erythroid response to epoetin alpha as a single agent versus in combination with granulocyte- or granulocyte-macrophage-colony-stimulating factor in myelodysplastic syndromes using a meta-analysis approach. Cancer. 2009;115:706–715
- . Interleukin-3 in the treatment of myelodysplastic syndromes. Int J Clin Lab Res. 1992;22:125–128
- Aberrant promotor methylation in MDS hematopoietic cells during in vitro lineage specific differentiation is differently associated with DNMT isoforms. Leuk Res. 2009;33:434–442
- . Valproic acid for the treatment of myeloid malignancies. Cancer. 2007;110:943–954
- . Measurement of serum cytokine levels in patients with myelodysplastic syndromes. Leukemia. 1992;6:1268–1272
- . Successful treatment with cyclosporine of sodium valproate-induced pure red cell aplasia. Rinsho Ketsueki. 2005;46:1114–1117
- . Trilineage hematopoietic toxicity associated with valproic acid therapy. J Pediatr Hematol Oncol. 1997;19:73–76
PII: S0301-472X(10)00134-7
doi: 10.1016/j.exphem.2010.03.019
© 2010 ISEH - Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.
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Experimental Hematology
Volume 38, Issue 8
, Pages 685-695
, August 2010
