Experimental Hematology
Volume 38, Issue 7 , Pages 548-556 , July 2010

Fibrocytes in health and disease

  • Erica L. Herzog

      Affiliations

    • Department of Internal Medicine, Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Conn., USA
    • Corresponding Author InformationOffprint requests to: Erica L. Herzog, M.D., Ph.D., Section of Pulmonary and Critical Care Medicine, Department of Internal Medicine, 300 Cedar Street, TAC S431, P.O. Box 208057, New Haven, CT 06520-8057
  • ,
  • Richard Bucala

      Affiliations

    • Section of Rheumatology, Yale University School of Medicine, New Haven, Conn., USA

Received 19 February 2010 ,Revised 19 February 2010 ,Accepted 5 March 2010.

  • Image Result

    Electron micrograph of a fibrocyte in the dermis of a patient with nephrogenic systemic fibrosis (image provided by Shawn Cowper, M.D.).

    Electron micrograph of a fibrocyte in the dermis of a patient with nephrogenic systemic fibrosis (image provided by Shawn Cowper, M.D.).

  • Image Result

    Fibrocyte origin, differentiation, migration, and function. α-SMA = α−smooth muscle action; bFGF = basic fibroblast growth factor; TGF = transforming growth factor; GM-CSF = granulocyte-macrophage col

    Fibrocyte origin, differentiation, migration, and function. α-SMA = α−smooth muscle action; bFGF = basic fibroblast growth factor; TGF = transforming growth factor; GM-CSF = granulocyte-macrophage colony-stimulating factor; HGF = hepatocyte growth factor; IL = interleukin; M-CSF = macrophage colony-stimulating factor; MHCII = major hisocompatibility complex class II; MIP-1 = macrophage inflammatory protein-1; PDGF = platelet-derived growth factor; VEGF = vascular endothelial growth factor.

PII: S0301-472X(10)00081-0

doi: 10.1016/j.exphem.2010.03.004

Experimental Hematology
Volume 38, Issue 7 , Pages 548-556 , July 2010