Experimental Hematology
Volume 38, Issue 4 , Pages 259-269.e2, April 2010

Therapeutic efficacy of the pan-cdk inhibitor PHA-793887 in vitro and in vivo in engraftment and high-burden leukemia models

  • Rachele Alzani

      Affiliations

    • Nerviano Medical Sciences Srl, Business Unit Oncology, Nerviano, Italy
    • Drs. Alzani and Pedrini contributed equally to this work.
  • ,
  • Olga Pedrini

      Affiliations

    • Laboratory of Cellular Therapy “G. Lanzani,” USC Haematology, Ospedali Riuniti di Bergamo, Bergamo, Italy
    • Drs. Alzani and Pedrini contributed equally to this work.
  • ,
  • Clara Albanese

      Affiliations

    • Nerviano Medical Sciences Srl, Business Unit Oncology, Nerviano, Italy
  • ,
  • Roberta Ceruti

      Affiliations

    • Nerviano Medical Sciences Srl, Business Unit Oncology, Nerviano, Italy
  • ,
  • Alessia Casolaro

      Affiliations

    • Nerviano Medical Sciences Srl, Business Unit Oncology, Nerviano, Italy
  • ,
  • Veronica Patton

      Affiliations

    • Nerviano Medical Sciences Srl, Business Unit Oncology, Nerviano, Italy
  • ,
  • Francesco Colotta

      Affiliations

    • Nerviano Medical Sciences Srl, Business Unit Oncology, Nerviano, Italy
  • ,
  • Alessandro Rambaldi

      Affiliations

    • Laboratory of Cellular Therapy “G. Lanzani,” USC Haematology, Ospedali Riuniti di Bergamo, Bergamo, Italy
  • ,
  • Martino Introna

      Affiliations

    • Laboratory of Cellular Therapy “G. Lanzani,” USC Haematology, Ospedali Riuniti di Bergamo, Bergamo, Italy
  • ,
  • Enrico Pesenti

      Affiliations

    • Nerviano Medical Sciences Srl, Business Unit Oncology, Nerviano, Italy
  • ,
  • Marina Ciomei

      Affiliations

    • Nerviano Medical Sciences Srl, Business Unit Oncology, Nerviano, Italy
  • ,
  • Josée Golay

      Affiliations

    • Laboratory of Cellular Therapy “G. Lanzani,” USC Haematology, Ospedali Riuniti di Bergamo, Bergamo, Italy
    • Corresponding Author InformationOffprint requests to: Josée Golay, Ph.D., Laboratory of Cellular Therapy “G. Lanzani,” Ospedali Riuniti, c/o Presidio Matteo Rota, Via Garibaldi 11-13, 24128 Bergamo, Italy

Received 13 January 2010; received in revised form 8 February 2010; accepted 9 February 2010. published online 17 February 2010.

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 This article is dedicated to the memory of our colleague, Valter Croci.

PII: S0301-472X(10)00048-2

doi:10.1016/j.exphem.2010.02.004

Experimental Hematology
Volume 38, Issue 4 , Pages 259-269.e2, April 2010