Experimental Hematology
Volume 38, Issue 4 , Pages 301-310.e2 , April 2010

Hypoxia mediates low cell-cycle activity and increases the proportion of long-term–reconstituting hematopoietic stem cells during in vitro culture

  • Pernilla Eliasson

      Affiliations

    • Experimental Hematology Unit, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden
    • Corresponding Author InformationOffprint requests to: Pernilla Eliasson, Ph.D., Experimental Hematology Unit, Department of Clinical and Experimental Medicine, Linköping University, SE-581 85 Linköping, Sweden
    • ,
  • Matilda Rehn

      Affiliations

    • Lund Strategic Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden
    • ,
  • Petter Hammar

      Affiliations

    • Experimental Hematology Unit, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden
    • ,
  • Peter Larsson

      Affiliations

    • Radiation Physics, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, Linköping, Sweden
    • ,
  • Oksana Sirenko

      Affiliations

    • FibroGen Inc., San Francisco, Calif., USA
    • ,
  • Lee A. Flippin

      Affiliations

    • FibroGen Inc., San Francisco, Calif., USA
    • ,
  • Jörg Cammenga

      Affiliations

    • Lund Strategic Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden
    • ,
  • Jan-Ingvar Jönsson

      Affiliations

    • Experimental Hematology Unit, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

Received 14 July 2009 ,Revised 12 January 2010 ,Accepted 22 January 2010.

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PII: S0301-472X(10)00013-5

doi: 10.1016/j.exphem.2010.01.005

Experimental Hematology
Volume 38, Issue 4 , Pages 301-310.e2 , April 2010

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