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Experimental Hematology
Volume 38, Issue 1
, Pages 11-19
, January 2010
Quantification of transforming capacity and cooperation of defined genetic alterations in myeloid malignancies
References
- . Hematologic malignancies. Curr Opin Hematol. 2001;8:189–119
- . A cell type-specific constitutive point mutant of the common beta-subunit of the human granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5 receptors requires the GM-CSF receptor alpha-subunit for activation. J Biol Chem. 1999;274:8669–8677
- Extracellular KIT receptor mutants, commonly found in core binding factor AML, are constitutively active and respond to imatinib mesylate. Blood. 2005;106:3958–3961
- . Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity. EMBO J. 1995;14:5569–5578
- . Mutations in myeloid neoplasms. Diagn Mol Pathol. 2008;17:191–199
- H. MPLW515L mutation in acute megakaryoblastic leukaemia. Leukemia. 2009;23:852–855
- Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1. Nat Genet. 2004;36:624–630
- . Transcriptional dysregulation during myeloid transformation in AML. Oncogene. 2007;26:6829–6837
- . Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53. J Biol Chem. 2003;278:11731–11734
- Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3′-BCL11B enhancers and coregulation by PU.1 and HMGA1. Cancer Res. 2007;67:1461–1471
- . Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001;411:494–498
- . A system for stable expression of short interfering RNAs in mammalian cells. Science. 2002;296:550–553
- . Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA. Cell Cycle. 2003;2:251–257
- . Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors. Mol Ther. 2000;2:435–445
- . Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25:402–408
- Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity. Blood. 2006;108:2545–2553
- . A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001;29:e45
- . Design of 5′ untranslated sequences in retroviral vectors developed for medical use. J Virol. 1999;73:4083–4089
- . Genetics of myeloid malignancies- pathogenetic and clinical implications. J Clin Oncol. 2005;23:6285–6295
- Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia. N Engl J Med. 2008;358:1909–1918
- . Expression of adaptor protein Lnk in leukemia cells. Exp Hematol. 2009;37:585–592
- . Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell. 1997;88:593–602
PII: S0301-472X(09)00397-X
doi: 10.1016/j.exphem.2009.10.006
© 2010 ISEH - Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.
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Experimental Hematology
Volume 38, Issue 1
, Pages 11-19
, January 2010
