Experimental Hematology
Volume 37, Issue 11 , Pages 1364-1377.e4 , November 2009

Ex vivo expansion of human hematopoietic stem cells by a small-molecule agonist of c-MPL

  • Taito Nishino

      Affiliations

    • Research Promotion and Coordination Department, Nissan Chemical Industries, Tokyo, Japan
  • ,
  • Katsuaki Miyaji

      Affiliations

    • Synthesis Research Department, Chemical Research Laboratories, Nissan Chemical Industries, Chiba, Japan
  • ,
  • Norihisa Ishiwata

      Affiliations

    • Pharmaceutical Research Department, Biological Research Laboratories, Nissan Chemical Industries, Saitama, Japan
  • ,
  • Kazutaka Arai

      Affiliations

    • Research Promotion and Coordination Department, Nissan Chemical Industries, Tokyo, Japan
  • ,
  • Makiko Yui

      Affiliations

    • ReproCELL Inc., Tokyo, Japan
    • Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan
  • ,
  • Yasuyuki Asai

      Affiliations

    • ReproCELL Inc., Tokyo, Japan
  • ,
  • Hiromitsu Nakauchi

      Affiliations

    • Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, University of Tokyo, Japan
  • ,
  • Atsushi Iwama

      Affiliations

    • Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan
    • Corresponding Author InformationOffprint requests to: Atsushi Iwama, M.D., Ph.D., Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670 Japan

Received 13 July 2009 ,Revised 31 August 2009 ,Accepted 2 September 2009.

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PII: S0301-472X(09)00360-9

doi: 10.1016/j.exphem.2009.09.001

Experimental Hematology
Volume 37, Issue 11 , Pages 1364-1377.e4 , November 2009