Experimental Hematology
Volume 37, Issue 6 , Pages 659-672 , June 2009

Detection and treatment of molecular relapse in acute myeloid leukemia with RUNX1 (AML1), CBFB, or MLL gene translocations: Frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression

  • Michael Doubek

      Affiliations

    • Department of Internal Medicine-Hematooncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • ,
  • Ivo Palasek

      Affiliations

    • Department of Internal Medicine-Hematooncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • ,
  • Zdenek Pospisil

      Affiliations

    • Department of Mathematics and Statistics, Faculty of Science, Masaryk University, Brno, Czech Republic
  • ,
  • Marek Borsky

      Affiliations

    • Department of Internal Medicine-Hematooncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • ,
  • Martin Klabusay

      Affiliations

    • Department of Internal Medicine-Hematooncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • ,
  • Yvona Brychtova

      Affiliations

    • Department of Internal Medicine-Hematooncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • ,
  • Tomas Jurcek

      Affiliations

    • Department of Internal Medicine-Hematooncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • ,
  • Ivana Jeziskova

      Affiliations

    • Department of Internal Medicine-Hematooncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • ,
  • Marta Krejci

      Affiliations

    • Department of Internal Medicine-Hematooncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • ,
  • Dana Dvorakova

      Affiliations

    • Department of Internal Medicine-Hematooncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
  • ,
  • Jiri Mayer

      Affiliations

    • Department of Internal Medicine-Hematooncology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
    • Corresponding Author InformationOffprint requests to: Jiri Mayer, M.D., Ph.D., Department of Internal Medicine–Hematooncology, University Hospital and Medical Faculty of Masaryk University, Jihlavska 20, 62500 Brno, Czech Republic

Received 25 November 2008 ,Revised 26 February 2009 ,Accepted 10 March 2009.

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PII: S0301-472X(09)00088-5

doi: 10.1016/j.exphem.2009.03.004

Experimental Hematology
Volume 37, Issue 6 , Pages 659-672 , June 2009