Experimental Hematology
Volume 36, Issue 12 , Pages 1642-1647 , December 2008

Proteomic study of the impact of the JAK2–V617F mutation on the phenotype of essential thrombocythemia

  • Pascal Mossuz

      Affiliations

    • Laboratoire d'hématologie cellulaire et moléculaire, DBPC, CHU Grenoble, France
    • Grenoble Institut des Neurosciences− GIN Centre de Recherche Inserm U 836–Equipe 7, France
    • Corresponding Author InformationOffprint requests to: Pascal Mossuz, M.D., Ph.D., Laboratoire d'hématologie cellulaire et moléculaire, CHU Grenoble, BP217 X, 38043 Grenoble Cedex, France
    • ,
  • Marie Arlotto

      Affiliations

    • Grenoble Institut des Neurosciences− GIN Centre de Recherche Inserm U 836–Equipe 7, France
    • ,
  • Sylvie Hermouet

      Affiliations

    • Laboratoire d'hématologie, CHU Nantes, France
    • ,
  • Ali Bouamrani

      Affiliations

    • Grenoble Institut des Neurosciences− GIN Centre de Recherche Inserm U 836–Equipe 7, France
    • ,
  • Eric Lippert

      Affiliations

    • Laboratoire d'hématologie, CHU Bordeaux, France
    • ,
  • François Girodon

      Affiliations

    • Laboratoire d'hématologie, CHU Dijon, France
    • ,
  • Irène Dobo

      Affiliations

    • Laboratoire d'hématologie, CHU Angers, France
    • ,
  • Praloran Vincent

      Affiliations

    • Laboratoire d'hématologie, CHU Bordeaux, France
    • ,
  • Jean Yves Cahn

      Affiliations

    • Département d'hématologie oncologie, CHU Grenoble, Université Joseph Fourier Grenoble, France
    • ,
  • François Berger

      Affiliations

    • Grenoble Institut des Neurosciences− GIN Centre de Recherche Inserm U 836–Equipe 7, France

Received 25 April 2008 ,Revised 17 July 2008 ,Accepted 31 July 2008.

References 

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  21. Scott LM, Scott MA, Campbell PJ, Green AR. Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not n essential thrombocythemia. Blood. 2006;108:2435–2437
  22. Yamamoto G, Nannya Y, Kato M, et al. Highly sensitive method for genome wide detection of allelic composition in non–paired, primary tumor specimens by use of affymetrix single nucleotide–polymorphism genotyping microarrays. Am J Hum Genet. 2007;81:114–126
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PII: S0301-472X(08)00390-1

doi: 10.1016/j.exphem.2008.07.013

Experimental Hematology
Volume 36, Issue 12 , Pages 1642-1647 , December 2008

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