« Previous
Next »
Experimental Hematology
Volume 36, Issue 12
, Pages 1673-1681.e1
, December 2008
Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma
References
- . Multiple myeloma: increasing evidence for a multistep transformation process. Blood. 1998;91:3–21
- . Chromosome translocations in multiple myeloma. Oncogene. 2001;20:5611–5622
- . Frequent hypermethylation of p16 and p15 genes in multiple myeloma. Blood. 1997;89:2500–2506
- . Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies. Blood. 1999;93:4347–4353
- . SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma. Blood. 2003;101:2784–2788
- . Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma. Leukemia. 2007;21:2527–2536
- . The growing family of interferon regulatory factors. Cytokine Growth Factor Rev. 1997;8:293–312
- Interferon regulatory factors: the next generation. Gene. 1999;237:1–14
- . IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev. 2003;17:1703–1708
- Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination. Nat Immunol. 2006;7:773–782
- Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma. Nat Genet. 1997;17:226–230
- Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell. 1996;87:307–317
- Lack of interferon consensus sequence binding protein (ICSBP) transcripts in human myeloid leukemias. Blood. 1998;91:22–29
- Disruption of the B-cell specific transcriptional program in HHV-8 associated primary effusion lymphoma cell lines. Oncogene. 2003;22:964–973
- Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein. J Exp Med. 2006;203:63–72
- Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells. Cancer Res. 2007;67:3301–3309
- Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein. J Exp Med. 1999;190:411–421
- . Established immunoglobulin producing myeloma (IgE) and lymphoblastoid (IgG) cell lines from an IgE myeloma patient. Clin Exp Immunol. 1970;7:477–489
- . Multiple myeloma cell lines. In: Palsson JRW editors. Human Cell Culture vol. 3. Dordrecht/Boston/London: Multiple myeloma cell lines; 2000;p. 81–156
- . Human plasmacytoma with an unusual karyotype growing in vitro and producing light-chain immunoglobulin. Lancet. 1982;1(8278):931–933
- . Establishment and characterization of a CD5 positive, immunosuppressive human myeloma cell line. Leukemia. 1990;4:775–780
- . Factors affecting the in vitro evolution of a myeloma cell line. Leukemia. 1992;6:940–947
- Long-term cultivation of plasma cell leukemia cells and autologous lymphoblasts (LCL) in vitro: a comparative study. Blut. 1978;36:331–338
- . The establishment of an interleukin-6-dependent myeloma cell line (FLAM-76) carrying t(11;14)(q13;q32) chromosome abnormality from an aggressive nonsecretory plasma cell leukemia. Cancer. 1992;70:1528–1535
- The human myeloma cell line LP-1: a versatile model in which to study early plasma-cell differentiation and c-myc activation. Blood. 1989;73:1020–1027
- . Production of free light chains of immunoglobulin by a hematopoietic cell line derived from a patient with multiple myeloma. Proc Soc Exp Biol Med. 1967;125:1246–1250
- . Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int J Cancer. 1976;17:565–577
- . Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line. J Exp Med. 1980;152:1709–1719
- . Establishment and characterization of an Epstein-Barr virus (EBC)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt's lymphoma. Biomedicine. 1975;22:276–284
- . Chromosome evolution of near-haploid clones in an established human acute lymphoblastic leukemia cell line (NALM-16). J Natl Cancer Inst. 1980;64:485–493
- . Establishment and characterization of human B cell precursor-leukemia cell lines. Leuk Res. 1998;22:567–579
- T cell-replacing factor- (TRF) induced IgG secretion in a human B blastoid cell line and demonstration of acceptors for TRF. J Immunol. 1981;127:412–416
- . Phenotypic and cytogenetic characteristics of human B-lymphoid cell lines and their relevance for the etiology of Burkitt's lymphoma. Adv Cancer Res. 1982;37:319–380
- . Inhibition of monocytic differentiation by phosphorylation-deficient Stat1 is associated with impaired expression of Stat2, ICSBP/IRF8 and C/EBPepsilon. Scand J Immunol. 2006;64:271–279
- ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia. 2004;6:1–6
- Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells. Blood. 2002;99:1745–1757
- An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes. Proc Natl Acad Sci U S A. 1990;87:3743–3747
- . The epigenetic progenitor origin of human cancer. Nat Rev Genet. 2006;7:21–33
- . Gene expression profiling of plasma cells and plasmablasts: toward a better understanding of the late stages of B-cell differentiation. Blood. 2003;102:592–600
- . Methyl-CpG-binding proteins. Targeting specific gene repression. Eur J Biochem. 2001;268:1–6
- . Increase in interleukin 6 (IL-6) and IL-6 receptor expression in a human multiple myeloma cell line, U-266, during long-term in vitro culture and the development of a possible autocrine IL-6 loop. Leukemia. 1992;6:310–318
- Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet. 2007;39:232–236
- A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet. 2007;39:237–242
- . Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet. 1999;21:103–107
PII: S0301-472X(08)00386-X
doi: 10.1016/j.exphem.2008.08.001
© 2008 ISEH - Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Experimental Hematology
Volume 36, Issue 12
, Pages 1673-1681.e1
, December 2008
