Experimental Hematology
Volume 36, Issue 11 , Pages 1567-1571 , November 2008

Assessment of the role of timing of second transplantation in multiple myeloma by multistate modeling

  • Simona Iacobelli

      Affiliations

    • Dipartimento Scienze per la Salute, University of Molise, Italy
    • EBMT CLWP Office, LUMC, Leiden, The Netherlands
    • ,
  • Jane Apperley

      Affiliations

    • Hematology Department, Hammersmith Hospital, London, UK
    • ,
  • Curly Morris

      Affiliations

    • Department of Haematology, Belfast City Hospital, Belfast, UK
    • Corresponding Author InformationOffprint requests to: Curly Morris, M.D., Department of Haematology, Belfast City Hospital, Lisburn Road, Belfast, BT9 7AB, UK

Received 21 March 2008 ,Revised 29 May 2008 ,Accepted 17 June 2008.

References 

  1. Attal M, Harousseau JL, Facon T, et al. Intergroup Francophone du Myelome: single versus double autologous stem cell transplantation for multiple myeloma. N Engl J Med. 2003;349:2495–2502
  2. Morris C, Iacobelli S, Brand R, et al. Benefit and timing of second transplantations in multiple myeloma: clinical findings and methodological limitations in a European Group for Blood and Marrow Transplantation registry study. J Clin Oncol. 2004;22:1674–1681
  3. Crowley J, Hu M. Covariance analysis of heart transplant data. JASA. 1997;72:27–39
  4. Aitkin M, Laird N, Francis B. A reanalysis of the Stanford heart transplant data. JASA. 1983;78:264–274
  5. Keiding N, Klein JP, Horowitz MM. Multi-state models and outcome prediction in bone marrow transplantation. Stat Med. 2001;20:1871–1885
  6. Klein JP, Keiding N, Copelan EA. Plotting summary predictions in multistate survival models: probabilities of relapse and death in remission for bone marrow transplantation patients. Stat Med. 1994;13:2315–2332
  7. Child JA, Morgan GJ, Davies FE, et al. Medical research Council Adult Leukemia Working Party: High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med. 2003;348:1875–1883
  8. Gratwohl A, Baldomero H, Frauendorfer K, et al. Results of the EBMT activity surey 2005 on haematopoietic stem cell transplantation: focus on increasing use of unrelated donors. Bone Marrow Transplant. 2007;39:71–87
  9. Cavo M, Tosi P, Zamagni E, et al. Prospective randomized study of single compared with double autologous stem cell transplantation for Multiple Myeloma: Bologna 96 clinical study. J Clin Oncol. 2007;25:2434–2441
  10. Sonneveld P, Van Der Holt B, Segeren CM, et al. Intermediate-dose Melphalan compared with myeloablative treatment in multiple myeloma: long-term follow-up of the Deutch Cooperative Group HOVON 24 trial. Haematologica. 2007;92:928–935
  11. Barlogie B, Jagannath S, Vesole DH, et al. Superiority of tandem autologous transplantation over standard therapy for previously untreated Multiple Myeloma. Blood. 1997;39:789–793
  12. Barlogie B, Tricot G, van Rhee F, et al. Long-term outcome results of the first tandem autotransplant trial for multiple myeloma. Br J Haematol. 2006;135:158–164

PII: S0301-472X(08)00304-4

doi: 10.1016/j.exphem.2008.06.007

Experimental Hematology
Volume 36, Issue 11 , Pages 1567-1571 , November 2008

Article Tools

* Image Usage & Resolution