Experimental Hematology
Volume 36, Issue 9 , Pages 1073-1077 , September 2008

Fetal-maternal microchimerism in normal parous females and parous female cancer patients

Received 21 December 2007 ,Revised 26 March 2008 ,Accepted 27 March 2008.

References 

  1. Bianchi D, Zickwolf G, Weil G, Sylvester S, DeMaria M. Male fetal progenitor cells persist in maternal blood for as long as 27 years post-partum. Proc Natl Acad Sci U S A. 1996;93:705–708
  2. Zhong X, Holzgreve W, Hahn S. Direct quantification of fetal cells in maternal blood by real-time PCR. Prenatal Diagn. 2006;26:850–854
  3. Adams K, Lambert N, Heimfeld S, et al. Male DNA in female donor apheresis and CD34-enriched products. Blood. 2003;102:3845–3847
  4. Evans P, Lambert N, Maloney S, Furst D, Moore J, Nelson J. Long-term fetal microchimerism in peripheral blood mononuclear cell subsets in healthy women and women with scleroderma. Blood. 1999;93:2033
  5. Nelson J. Microchimerism and the pathogenesis of systemic sclerosis. Curr Opin Rheumatol. 1998;10:564–571
  6. Nelson J. Microchimerism in human health and disease. Autoimmunity. 2003;36:5–9
  7. Lambert N, Erickson T, Yan Z, et al. Quantification of maternal microchimerism by HLA-specific real time polymerase chain reaction: studies of healthy women and women with scleroderma. Arthritis Rheum. 2004;50:906–914
  8. Sarkar K, Miller F. Possible roles and determinants of microchimerism in autoimmune and other disorders. Autoimmun Rev. 2004;3:454–463
  9. Shimazaki C, Ochiai N, Uchida R, et al. Non-T-cell-depleted HLA haploidentical stem cell transplantation in advanced hematologic malignancies based on the feto-maternal microchimerism. Blood. 2003;101:3334–3336
  10. Teshima T, Matsuoka K, Ichinohe T. Impact of fetal-maternal tolerance in hematopoietic stem cell transplantation. Arch Immunol Ther Exp (Warsz). 2006;54:165–172
  11. Ichinohe T, Teshima T, Matsuoka K, Maruya E, Saji H. Fetal-maternal microchimerism: impact on hematopoietic stem cell transplantation. Curr Opin Immunol. 2005;17:546–552
  12. Utter G, Reed W, Lee T, Busch M. Transfusion-associated microchimerism. Vox Sanguinis. 2007;93:188–195
  13. Yan Z, Lambert N, Guthrie K, et al. Male microchimerism in women without sons: Quantitative assessment and correlation with pregnancy history. Am J Med. 2005;118:899–906
  14. Gadi V, Nelson J. Fetal microchimerism in women with breast cancer. Cancer Res. 2007;67:9035–9038

PII: S0301-472X(08)00153-7

doi: 10.1016/j.exphem.2008.03.020

Experimental Hematology
Volume 36, Issue 9 , Pages 1073-1077 , September 2008