Experimental Hematology
Volume 36, Issue 7 , Pages 769-770 , July 2008

Myeloprotection following cytotoxic damage: The sooner the better

  • Francis Hérodin, Ph.D.

      Affiliations

    • Corresponding Author InformationOffprint requests to: Francis Hérodin, Ph.D. Radiohematology Unit, Centre de Recherches du Service de Santé des Armées, La Tronche 38702, France.
  • ,
  • Michel Drouet, M.D., Ph.D.

References 

  1. Yankelevich M, Goodell MA, Kaplan J. Efficacy of delayed administration of postchemotherapy granulocyte colony-stimulating factor: evidence from murine studies of bone marrow cell kinetics. Exp Hematol. 2008;36:9–16
  2. Drouet M, Mathieu J, Grenier N, Multon E, Sotto JJ, Hérodin F. The reduction of in vitro radiation-induced Fas-related apoptosis in CD34+ progenitor cells by SCF, Flt-3 ligand, TPO and IL-3 in combination resulted in CD34+ cell proliferation and differentiation. Stem Cells. 1999;17:273–285
  3. Hérodin F, Bourin P, Mayol JF, Lataillade JJ, Drouet M. Short-term injection of antiapoptotic cytokine combinations soon after lethal gamma irradiation promotes survival. Blood. 2003;101:2609–2616
  4. Drouet M, Mourcin F, Grenier N, et al. Single administration of stem cell factor, FLT-3 ligand, megakaryocyte growth and development factor and interleukin-3 in combination soon after irradiation prevents nonhuman primates from myelosuppression: long-term follow-up of hematopoiesis. Blood. 2004;103:878–885
  5. Hérodin F, Grenier N, Drouet M. Revisiting therapeutic strategies in radiation casualties. Exp Hematol. 2007;35(4 Suppl 1):28–33
  6. Shibuya K, Akahori H, Takahashi K, Tahara E, Kato T, Miyazaki H. Multilineage hematopoietic recovery by a single injection of pegylated recombinant human megakaryocyte growth and development factor in myelosuppressed mice. Blood. 1998;91:37–45

PII: S0301-472X(08)00071-4

doi: 10.1016/j.exphem.2008.02.005

Experimental Hematology
Volume 36, Issue 7 , Pages 769-770 , July 2008