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Experimental Hematology
Volume 35, Issue 5
, Pages 702-711
, May 2007
V617F JAK-2 mutation in patients with essential thrombocythemia: relation to platelet, granulocyte, and plasma hemostatic and inflammatory molecules
References
- . Chronic myeloid disorders, excluding CML. In: Degos L, Linch DC, Löwenberg B editor. Textbook of Malignant Hematology. London: Martin Dunitz Ltd.; 1999;p. 847–869
- . Thrombosis and haemorrhage in polycythemia vera and essential thrombocythemia. Br J Haematol. 2005;128:275–290
- . Polycythemia vera: the natural history of 1213 patients followed over 20 years. Ann Intern Med. 1995;123:656–664
- . Pathophysiology and treatment of platelet-mediated microvascular disturbances, major thrombosis and bleeding complications in essential thrombocythaemia and polycythaemia vera. Platelets. 2004;15:67–84
- Leukocytosis as a major thrombotic risk factor in patients with polycythemia vera. Blood. 2007;15:2446–2452
- Leukocytosis is a risk factor for thrombosis in essential thrombocythemia: interaction with treatment, standard risk factors and Jak2 mutation status. Blood. 2007;15:2310–2313
- . Platelets and thrombosis in myeloproliferative disorders. Hematology. 2005;409–415
- . Pathogenesis of thrombosis in essential thrombocythemia and polycythemia vera: the role of neutrophils. Semin Hematol. 2005;42:239–247
- Increased circulating platelet-leukocyte aggregates in myeloproliferative disorders is correlated to previous thrombosis, platelet activation and platelet count. Eur J Haematol. 2001;66:143–151
- . Markers of platelet activation and platelet-leukocyte interaction in patients with myeloproliferative syndromes. Thromb Res. 2002;108:139–145
- Polymorphonuclear leukocyte activation and hemostasis in patients with essential thrombocythemia and polycythemia vera. Blood. 2000;96:4261–4266
- . Leukocyte-platelet interaction in patients with essential thrombocythemia and polycythemia vera. Exp Hematol. 2005;33:523–530
- Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet. 2005;365:1054–1061
- A gain-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med. 2005;352:1779–1790
- A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005;434:1144–1148
- Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 2005;7:387–397
- Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study. Lancet. 2005;366:1945–1953
- . Essential thrombocythemia beyond the first decade: expectancy, long-term complication rates, and prognostic factors. Mayo Clinic Proc. 2006;81:159–166
- . Increased platelet and leukocyte activation as contributing mechanisms for thrombosis in essential thrombocythemia and correlation with the JAK2 mutational status. Haematologica. 2006;91:169–175
- Relation between JAK2 (V617F) mutation status, granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders. Blood. 2006;107:3676–3682
- Cellular inflammatory response to persistent localized Staphylococcus aureus infection: phenotypical and functional characterization of polymorphonuclear neutrophils (PMN). Clin Exp Immunol. 2006;143:70–77
- . Formation of mixed platelet-PMN leukocyte aggregates in the platelet function analyzer (PFA-100) device. Thromb Haemost. 2007;97:156–157
- . Platelet dysfunction in primary thrombocythemia using the platelet function analyzer, PFA-100. Am J Clin Pathol. 2005;123:772–777
- . Role of tissue factor in hemostasis, thrombosis, and vascular development. Arterioscler Thromb Vasc Biol. 2004;24:1015–1022
- Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets. FASEB J. 2003;17:476–478
- Platelet activation induces cell-surface immunoreactive tissue factor expression, which is modulated differently by antiplatelet drugs. Arterioscler Thromb Vasc Biol. 2003;23:1690–1696
- . The presence and release of tissue factor from human platelets. Platelets. 2002;13:247–253
- . Increased platelet activation and abnormal glycoprotein content and redistribution in myeloproliferative disorders. Br J Haematol. 2000;110:116–124
- . P-selectin in haemostasis. Br J Haematol. 2004;126:298–306
- . Role of platelet P-selectin and microparticles PSGL-1 in thrombus formation. Trends Mol Med. 2004;10:171–178
- . Links The P-selectin, tissue factor, coagulation triad. J Thromb Haemost. 2005;3:1590–1596
- . Platelet membrane abnormalities in myeloproliferative disorders: decrease in glycoproteins Ib and IIb/IIIa complex is associated with deficient receptor function. Br J Haematol. 1989;73:369–374
- . Increased platelet CD36 constitutes a common marker in myeloproliferative disorders. Br J Haematol. 1995;91:618–624
- Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin. J Exp Med. 2003;197:1585–1598
- P-selectin and leukocyte microparticles are associated with venous thrombogenesis. J Vasc Surg. 2003;38:1075–1089
- Transfer of tissue factor from leukocytes to platelets is mediated by CD15 and tissue factor. Blood. 2000;96:170–175
- Links Effects of platelet binding on whole blood flow cytometry assays of monocyte and neutrophil procoagulant activity. J Thromb Haemost. 2005;3:2563–2570
- . Tissue factor in neutrophils. Thromb Haemost. 2000;83:802
- . Tissue factor in neutrophils: yes. J Thromb Haemost. 2004;2:214–217
- . Tissue factor in neutrophils: no. J Thromb Haemost. 2004;2:218–220
- Inhibition of tissue factor expression by hydroxyurea in polymorphonuclear leukocytes from patients with myeloproliferative disorders: a new effect for an old drug?. J Thromb Haemost. 2006;4:2593–2598
- Human polymorphonuclear leukocytes produce and express functional tissue factor upon stimulation. J Thromb Haemost. 2006;4:1323–1330
- . Assessment of endothelial damage and dysfunction: observations in relation to heart failure. QJM. 2003;96:253–267
PII: S0301-472X(07)00097-5
doi: 10.1016/j.exphem.2007.01.053
© 2007 International Society for Experimental Hematology. Published by Elsevier Inc. All rights reserved.
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Experimental Hematology
Volume 35, Issue 5
, Pages 702-711
, May 2007
