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Experimental Hematology
Volume 35, Issue 3
, Pages 358-367
, March 2007
Stem cell transplantation demonstrates that Sox6 represses εy globin expression in definitive erythropoiesis of adult mice
References
- A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature. 1990;346:245–250
- A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif. Nature. 1990;346:240–244
- . SRY, like HMG1, recognizes sharp angles in DNA. EMBO J. 1992;11:4497–4506
- DNA binding and bending properties of the post-meiotically expressed Sry-related protein Sox-5. Nucleic Acids Res. 1994;22:3339–3346
- . Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytes. EMBO J. 1993;12:3847–3854
- . Architectural transcription factors: proteins that remodel DNA. Cell. 1997;88:733–736
- . Architectural transcription factors. Science. 1994;264:1100–1101
- . The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse. Nucleic Acids Res. 1995;23:3365–3372
- Sox6 overexpression causes cellular aggregation and the neuronal differentiation of P19 embryonic carcinoma cells in the absence of retinoic acid. FEBS Lett. 2004;560:192–198
- Suppression of Sox6 in P19 cells leads to failure of neuronal differentiation by retinoic acid and induces retinoic acid-dependent apoptosis. FEBS Lett. 2004;577:60–66
- . Quantitative analysis of gene expression in living adult neural stem cells by gene trapping. Nat Methods. 2005;2:363–370
- . A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J. 1998;17:5718–5733
- The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001;1:277–290
- . Regulation of type-II collagen gene expression during human chondrocyte de-differentiation and recovery of chondrocyte-specific phenotype in culture involves Sry-type high-mobility-group box (SOX) transcription factors. Biochem J. 2001;360:461–470
- Induction of the Sry-related factor SOX6 contributes to bone morphogenetic protein-2-induced chondroblastic differentiation of C3H10T1/2 cells. Mol Endocrinol. 2003;17:1332–1343
- . Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death. Proc Natl Acad Sci U S A. 2000;97:4180–4185
- . Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005;234:301–311
- . Differential expression of novel potential regulators in hematopoietic stem cells. PLoS Genet. 2005;1:e28
- Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse development. Blood. 2006;108:1198–1207
- Sox6 directly silences epsilon globin expression in definitive erythropoiesis. PLoS Genet. 2006;2:e14
- . Understanding fetal globin gene expression: a step towards effective HbF reactivation in haemoglobinopathies. Br J Haematol. 1998;102:415–422
- . Mechanisms of developmental control of transcription in the murine alpha- and beta-globin loci. Genes Dev. 1999;13:112–124
- . Evidence that DNase I hypersensitive site 5 of the human beta-globin locus control region functions as a chromosomal insulator in transgenic mice. Nucleic Acids Res. 2002;30:2484–2491
- . Ontogeny of the haemopoietic system: yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo. Br J Haematol. 1970;18:279–296
- . Role of stem cell migration in initiation of mouse foetal liver haemopoiesis. Nature. 1975;258:726–728
- . Mouse embryonic hematopoiesis. Trends Genet. 1995;11:359–366
- . Autonomous developmental control of human embryonic globin gene switching in transgenic mice. Science. 1990;250:1147–1149
- . Chromatin structure and control of beta-like globin gene switching. Exp Biol Med (Maywood). 2002;227:683–700
- . Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice. Nature. 1999;398:344–348
- . Expansion of hematopoietic stem cells in the developing liver of a mouse embryo. Blood. 2000;95:2284–2288
- . Prevention of graft-versus-host disease (GVHD) by elimination of recipient-reactive donor T cells with recombinant toxins that target the interleukin 2 (IL-2) receptor. Bone Marrow Transplant. 1999;23:137–144
- . Splenic erythropoiesis in polycythemic response of the rat to high-altitude exposure. J Appl Physiol. 1980;48:857–861
- . Interaction of stem cell factor and its receptor c-kit mediates lodgment and acute expansion of hematopoietic cells in the murine spleen. Blood. 1996;88:75–81
- . Morphological study of the transition of haematopoietic sites in the developing mouse during the peri-natal period. Anat Histol Embryol. 2006;35:235–240
- . The polychromatophilic erythrocyte. Am J Clin Pathol. 1972;57:471–477
- . A human embryonic hemoglobin inhibits Hb S polymerization in vitro and restores a normal phenotype to mouse models of sickle cell disease. Proc Natl Acad Sci U S A. 2002;99:10635–10640
PII: S0301-472X(06)00703-X
doi: 10.1016/j.exphem.2006.11.009
© 2007 International Society for Experimental Hematology. Published by Elsevier Inc. All rights reserved.
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Experimental Hematology
Volume 35, Issue 3
, Pages 358-367
, March 2007
