Experimental Hematology
Volume 35, Issue 3 , Pages 407-415 , March 2007

Monitoring of disease progression by bioluminescence imaging and magnetic resonance imaging in an animal model of hematologic malignancy

  • Yusuke Inoue

      Affiliations

    • Department of Radiology, Institute of Medical Science, University of Tokyo, Tokyo, Japan
    • Corresponding Author InformationOffprint requests to: Yusuke Inoue, M.D., Department of Radiology, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
  • ,
  • Kiyoko Izawa

      Affiliations

    • Division of Molecular Therapy, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan
  • ,
  • Arinobu Tojo

      Affiliations

    • Division of Molecular Therapy, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan
  • ,
  • Yukihiro Nomura

      Affiliations

    • Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  • ,
  • Rieko Sekine

      Affiliations

    • Division of Molecular Therapy, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan
  • ,
  • Naoki Oyaizu

      Affiliations

    • Department of Laboratory Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan
  • ,
  • Kuni Ohtomo

      Affiliations

    • Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan

Received 7 July 2006 ,Revised 13 November 2006 ,Accepted 13 November 2006.

References 

  1. Contag CH, Jenkins D, Contag PR, Negrin RS. Use of reporter genes for optical measurements of neoplastic disease in vivo. Neoplasia. 2000;2:41–52
  2. Edinger M, Cao YA, Hornig YS, et al. Advancing animal models of neoplasia through in vivo bioluminescence imaging. Eur J Cancer. 2002;38:2128–2136
  3. Day JC, Tisi LC, Bailey MJ. Evolution of beetle bioluminescence: the origin of beetle luciferin. Luminescence. 2004;19:8–20
  4. Choy G, O'Connor S, Diehn FE, et al. Comparison of noninvasive fluorescent and bioluminescent small animal optical imaging. Biotechniques. 2003;35:1022–1030
  5. Paroo Z, Bollinger RA, Braasch DA, et al. Validating bioluminescence imaging as a high-throughput, quantitative modality for assessing tumor burden. Mol Imaging. 2004;3:117–124
  6. Nogawa M, Yuasa T, Kimura S, et al. Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models. Cancer Lett. 2005;217:243–253
  7. Rehemtulla A, Stegman LD, Cardozo SJ, et al. Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging. Neoplasia. 2000;2:491–495
  8. Szentirmai O, Baker CH, Lin N, et al. Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect. Neurosurgery. 2006;58:365–372
  9. Nyati MK, Symon Z, Kievit E, et al. The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model. Gene Ther. 2002;9:844–849
  10. Smakman N, Martens A, Kranenburg O, Borel Rinkes IH. Validation of bioluminescence imaging of colorectal liver metastases in the mouse. J Surg Res. 2004;122:225–230
  11. Mandl SJ, Mari C, Edinger M, et al. Multi-modality imaging identifies key times for annexin V imaging as an early predictor of therapeutic outcome. Mol Imaging. 2004;3:1–8
  12. Jenkins DE, Oei Y, Hornig YS, et al. Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis. Clin Exp Metastasis. 2003;20:733–744
  13. Scatena CD, Hepner MA, Oei YA, et al. Imaging of bioluminescent LNCaP-luc-M6 tumors: a new animal model for the study of metastatic human prostate cancer. Prostate. 2004;59:292–303
  14. Zeamari S, Rumping G, Floot B, Lyons S, Stewart FA. In vivo bioluminescence imaging of locally disseminated colon carcinoma in rats. Br J Cancer. 2004;90:1259–1264
  15. Edinger M, Cao YA, Verneris MR, Bachmann MH, Contag CH, Negrin RS. Revealing lymphoma growth and the efficacy of immune cell therapies using in vivo bioluminescence imaging. Blood. 2003;101:640–648
  16. Shah NP, Tran C, Lee FY, Chen P, Norris D, Sawyers CL. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science. 2004;305:399–401
  17. Wu KD, Cho YS, Katz J, et al. Investigation of antitumor effects of synthetic epothilone analogs in human myeloma models in vitro and in vivo. Proc Natl Acad Sci U S A. 2005;102:10640–10645
  18. Weisberg E, Manley PW, Breitenstein W, et al. Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer Cell. 2005;7:129–141
  19. Yoshimitsu M, Sato T, Tao K, et al. Bioluminescent imaging of a marking transgene and correction of Fabry mice by neonatal injection of recombinant lentiviral vectors. Proc Natl Acad Sci U S A. 2004;101:16909–16914
  20. Carlsen H, Moskaug JO, Fromm SH, Blomhoff R. In vivo imaging of NF-kappa B activity. J Immunol. 2002;168:1441–1446
  21. Inoue Y, Izawa K, Tojo A, Sekine R, Okubo T, Ohtomo K. Light emission requires exposure to the atmosphere in ex vivo bioluminescence imaging. Mol Imaging. 2006;5:53–56
  22. Haishi T, Uematsu T, Matsuda Y, Kose K. Development of a 1.0 T MR microscope using a Nd-Fe-B permanent magnet. Magn Reson Imaging. 2001;19:875–880
  23. Inoue Y, Nomura Y, Haishi T, et al. Imaging of living mice using a 1-T compact magnetic resonance imaging system. J Magn Reson Imaging. 2006;24:901–907
  24. Garbow JR, Kataoka M, Flye MW. MRI measurement of liver regeneration in mice following partial hepatectomy. Magn Reson Med. 2004;52:177–180
  25. Inderbitzin D, Gass M, Beldi G, et al. Magnetic resonance imaging provides accurate and precise volume determination of the regenerating mouse liver. J Gastrointest Surg. 2004;8:806–811
  26. Allegrini PR, Wachsmuth ED. Course of murine leukemia retrovirus infection determined in vivo by magnetic resonance imaging. Lab Invest. 1990;63:568–575
  27. Inoue Y, Tojo A, Sekine R, et al. In vitro validation of bioluminescent monitoring of disease progression and therapeutic response in leukaemia model animals. Eur J Nucl Med Mol Imaging. 2006;33:557–565
  28. Copelan EA, McGuire EA. The biology and treatment of acute lymphoblastic leukemia in adults. Blood. 1995;85:1151–1168
  29. Li S, Ilaria RL, Million RP, Daley GQ, Van Etten RA. The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity. J Exp Med. 1999;189:1399–1412
  30. Reimer P, Schneider G, Schima W. Hepatobiliary contrast agents for contrast-enhanced MRI of the liver: properties, clinical development and applications. Eur Radiol. 2004;14:559–578
  31. Rice BW, Cable MD, Nelson MB. In vivo imaging of light-emitting probes. J Biomed Opt. 2001;6:432–440
  32. El Hilali N, Rubio N, Martinez-Villacampa M, Blanco J. Combined noninvasive imaging and luminometric quantification of luciferase-labeled human prostate tumors and metastases. Lab Invest. 2002;82:1563–1571
  33. Honigman A, Zeira E, Ohana P, et al. Imaging transgene expression in live animals. Mol Ther. 2001;4:239–249
  34. Burgos JS, Rosol M, Moats RA, et al. Time course of bioluminescent signal in orthotopic and heterotopic brain tumors in nude mice. Biotechniques. 2003;34:1184–1188
  35. Kreft BP, Tanimoto A, Stark DD, et al. Enhancement of tumor-liver contrast-to-noise ratio with gadobenate dimeglumine in MR imaging of rats. J Magn Reson Imaging. 1993;3:41–49
  36. Kim YK, Lee JM, Kim CS. Gadobenate dimeglumine-enhanced liver MR imaging: value of dynamic and delayed imaging for the characterization and detection of focal liver lesions. Eur Radiol. 2004;14:5–13
  37. Gauvain KM, Garbow JR, Song SK, Hirbe AC, Weilbaecher K. MRI detection of early bone metastases in b16 mouse melanoma models. Clin Exp Metastasis. 2005;22:403–411

PII: S0301-472X(06)00702-8

doi: 10.1016/j.exphem.2006.11.006

Experimental Hematology
Volume 35, Issue 3 , Pages 407-415 , March 2007