Experimental Hematology
Volume 35, Issue 3 , Pages 434-442 , March 2007

Metalloprotease inhibitors block release of soluble CD27 and enhance the immune stimulatory activity of chronic lymphocytic leukemia cells

  • Kazunori Kato

      Affiliations

    • Division of Hematology/Oncology, Department of Medicine and the UCSD Human Gene Therapy Program, UCSD School of Medicine, La Jolla, Calif., USA
    • Department of Molecular Medicine, Sapporo Medical University, Sapporo, Japan
    • Corresponding Author InformationOffprint requests to: Kazunori Kato, Ph.D., Department of Molecular Medicine, Sapporo Medical University, South 1, West 17, Sapporo 060-8556, Japan
  • ,
  • Peter Chu

      Affiliations

    • Division of Hematology/Oncology, Department of Medicine and the UCSD Human Gene Therapy Program, UCSD School of Medicine, La Jolla, Calif., USA
  • ,
  • Satoshi Takahashi

      Affiliations

    • Division of Molecular Therapy, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan
  • ,
  • Hirofumi Hamada

      Affiliations

    • Department of Molecular Medicine, Sapporo Medical University, Sapporo, Japan
  • ,
  • Thomas J. Kipps

      Affiliations

    • Division of Hematology/Oncology, Department of Medicine and the UCSD Human Gene Therapy Program, UCSD School of Medicine, La Jolla, Calif., USA
    • Moores UCSD Cancer Center, La Jolla, Calif., USA

Received 8 May 2006 ,Revised 5 October 2006 ,Accepted 30 October 2006.

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PII: S0301-472X(06)00701-6

doi: 10.1016/j.exphem.2006.10.018

Experimental Hematology
Volume 35, Issue 3 , Pages 434-442 , March 2007