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Experimental Hematology
Volume 30, Issue 10
, Pages 1132-1138
, October 2002
Transforming growth factor-β1 augments granulocyte-macrophage colony-stimulating factor–induced proliferation of umbilical cord blood CD34+ cells with an associated tyrosine phosphorylation of STAT5
References
- Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical cord blood from an HLA-identical sibling. N Engl J Med. 1989;321:1174
- . Thrombopoietin directory and potently stimulates multilineage growth and progenitor cell expansion from primitive (CD34+CD38−) human bone marrow progenitor cells. J Immunol. 1997;158:5169
- . Quantitative analysis reveals expression of human hematopoietic repopulating cells after short-term ex vivo culture. J Exp Med. 1997;186:619
- . Proliferation of individual hematopoietic progenitors purified from umbilical cord blood. Exp Hematol. 1995;23:1453
- . In vitro self-renewal division of hematopoietic stem cells. J Exp Med. 2000;192:1281
- Human GM-CSF (molecular cloning of the complementary DNA and purification of the natural and recombinant proteins). Science. 1985;228:810
- . Molecular physiology of granulocyte-macrophage colony-stimulating factor. Blood. 1991;77:1131
- . The biology of granulocyte-macrophage colony-stimulating factor (effects on hematopoietic and nonhematopoietic cells). Dev Biol. 1992;151:352
- Signal transduction pathways in normal human monocytes stimulated by cytokines and mediators (comparative study with normal human neutrophils or transformed cells and the putative roles in functionality and cell biology). Exp Hematol. 1999;27:1063
- . In vitro analysis of STAT5 activation by granulocyte-macrophage colony-stimulating factor. Genes Cells. 2000;5:937
- . Differentiation-linked changes in granulocyte-macrophage colony-stimulating factor receptor mediated signaling in the HL-60 promyelocytic cell line. Br J Haematol. 1998;101:82
- . The transforming growth factor-beta family. Annu Rev Cell Biol. 1990;6:597
- . The TGF-β superfamily (new members, new receptors, and new genetic tests of function in different organisms). Genes Dev. 1994;8:133
- . Transforming growth factor β1 selectively regulates early murine hematopoietic progenitors and inhibits the growth of IL-3–dependent myeloid leukemia cell lines. J Exp Med. 1988;168:737
- Comparative effects of suppressive cytokines on isolated single CD34+++ stem/progenitor cells from human bone marrow and umbilical cord blood plated with and without serum. Exp Hematol. 1993;21:1442
- Specific dose-response effects of TGF-β1 on developmentally distinct hematopoietic stem/progenitor cells from umbilical cord blood. Hematol J. 2000;1:126
- . Stimulation of granulopoiesis by transforming growth factor β (synergy with granulocyte/macrophage-colony-stimulating factor). Proc Natl Acad Sci U S A. 1991;88:7190
- . TGF-β is a bidirectional modulator of cytokine receptor expression on murine bone marrow cells. J Immunol. 1993;151:4534
- . Establishment of a novel human myeloid leukemia cell line (FKH-1) with t(6;9) (p23;q34) and the expression of dek-can chimaeric transcript. Br J Haematol. 1998;102:1249
- . Establishment of a novel human acute myeloblastic leukemia cell line (YNH-1) with t(16;21), t(1;16) and 12q13 translocations. Leukemia. 1997;11:599
- M-07e human leukemic factor-dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM-CSF and IL-3. J Cell Physiol. 1990;145:458
- . Changes in signal transduction downstream from the granulocyte-macrophage colony-stimulating factor receptor during differentiation of primary hemopoietic cells. Exp Hematol. 1999;27:1077
- Transforming growth factor-β1 interferes with thrombopoietin-induced signal transduction in megakaryoblastic and erythroleukemic cells. Exp Hematol. 2001;29:602
- . TGF-β inhibits IL-12–induced activation of Jak-STAT pathway in T lymphocytes. J Immunol. 1998;161:1772
- Transforming growth factor β1 is significantly elevated in plasma of patients suffering from renal cell carcinoma. Cytokine. 1996;8:794
- . Increased granulopoiesis after sequential administration of transforming growth factor-β 1 and granulocyte-macrophage colony-stimulating factor. Exp Hematol. 1993;21:799
- Transforming growth factor beta 1 is an inducer of erythroid differentiation. J Exp Med. 1994;180:851
- . TGF-β1 drives and accelerates erythroid differentiation in the Epo-dependent UT-7 cell line even in the absence of erythropoietin. Exp Hematol. 2000;28:256
- Transforming growth factor inhibits erythropoiesis by blocking proliferation and accelerating differentiation of erythroid progenitors. Exp Hematol. 2000;28:885
- TGF-β1 promotes in vitro development of dendritic cells from CD34+ hemopoietic progenitors. J Immunol. 1996;157:1499
- . Expansion of dendritic cells derived from human CD34+ cells in static and continuous perfusion cultures. Br J Haematol. 1998;101:352
- Synergistic signaling in fetal brain by STAT3-Smad 1 complex bridged by p300. Science. 1999;284:479
- . Cross-talk between IL-6 and TGF-β signaling in hepatoma cells. FEBS Lett. 2001;492:247
- . Bidirectional effects of transforming growth factor β (TGF-β) on colony-stimulating factor–induced human myelopoiesis in vitro (differential effects of distinct TGF-β isoforms). Blood. 1991;78:2239
- . TGFβ signaling in growth control, cancer, and heritable disorders. Cell. 2000;103:295
- . Clinical-scale human umbilical cord blood cell expansion in a novel automated perfusion culture system. Bone Marrow Transplant. 1998;21:653
- . Ex vivo expansion of hematopoietic progenitor cells and mature cells. Exp Hematol. 2001;29:3
-
TGF-β1 maintains hematopoietic immaturity by a reversible negative control of cell cycle and induces CD34 antigen up-modulation.
J Cell Sci. 2000;113:383
- . Transforming growth factor beta 1 delays formation of granulocyte-macrophage colony-forming cells, but spares more primitive progenitors during ex vivo expansion of CD34+ haemopoietic progenitor cells. Br J Haematol. 1997;99:951
PII: S0301-472X(02)00902-5
© 2002 International Society for Experimental Hematology. Published by Elsevier Inc All rights reserved.
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Experimental Hematology
Volume 30, Issue 10
, Pages 1132-1138
, October 2002
